芝加哥——利他林作为注意力缺陷障碍的常用药,用于学龄前儿童是否安全?首次由政府组织的长期研究警告人们,该药对学龄前儿童有副作用,6岁以下儿童应慎用。
虽然严重的注意力缺陷障碍患儿可从利他林治疗中获益,但研究者认为学龄前儿童使用利他林还需严密观察,因为他们比年长的儿童更易产生副作用。
该研究包括了有严重行为问题(如挂在吊扇上、玩火等)的患儿。研究者说,对这些学龄前儿童来说,小剂量利他林治疗利大于弊。
大约有40%的患儿发生副作用,11%因易怒、体重下降、失眠、生长缓慢等问题而中途退出。在这项为期70个星期的研究发现,服用利他林的学龄前儿童身高和体重的增加值分别比预期值低半英寸和2英磅。
Posted on Fri, Oct. 20, 2006
Study warns of risks of preschool Ritalin
Associated Press
CHICAGO – Is it safe to give preschoolers Ritalin, the popular attention deficit disorder drug? The first long-term government study of that age group warns of side effects with the drug, which isn’t recommended for children younger than 6.
There were benefits for children who had severe ADHD, but the researchers said preschoolers on Ritalin need close monitoring because they’re more likely than older children to develop side effects.
The research involved children with severe behaviors that included hanging from ceiling fans and playing with fire. The researchers say the benefits of low-dose treatment outweigh the risks for these youngsters.
About 40 percent of children developed side effects and about 11 percent dropped out because of problems including irritability, weight loss, insomnia and slowed growth. Preschoolers on methylphenidate, or generic Ritalin, grew about a half-inch and gained about 2 pounds less than expected during the 70-week study.
The study appears in the November edition of the Journal of the American Academy of Child and Adolescent Psychiatry, www.jaacap.com.
http://www.fortwayne.com/mld/journalgazette/news/nation/15805876.htm
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作者: qcywh2000 译
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