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《综合内科学》杂志2006年11月刊上一篇文章报道，精神分裂症患者（不论男女）比正常人更易于患有46种常见慢性病中的一种或多种慢性病。

印地安纳大学医学院神经病学助教授兼Regenstrief研究所科学家，Caroline Carney Doebbeling医学博士认为，“心理和身体健康之间的相互关系还存在很多谜团，有待于进一步研究。”该项研究的第一作者Carney Doebbeling博士对入院和门诊的18—64岁700，000多例病人的保险索赔数额进行研究。她已在这一人群中研究了精神疾病与癌症、精神疾病与糖尿病的关系以及患有精神疾病的女性拍摄乳房X线照片的可能性。

在一项新的研究中，Carney Doebbeling及其同事指出，同正常人相比，精神分裂症患者更容易患有很多不同系统的疾病，如心血管、肺部、神经系统以及内分泌障碍性疾病。年轻的精神分裂症患者（平均年龄为40岁）中有三分之一已经患有三种及以上的慢性病，需要进行治疗。只有29%的精神分裂症患者，同对照组54％的人群一样，没有任何系统疾病出现。

除精神疾患外，生理疾病引发的问题是严重的，它影响患者的生活质量以及加重了患者的医疗开销。

“这项研究强调心理和生理疾病综合性治疗的必要性，指出慢性心理疾病会对生理健康产生长期负作用，”Carney Doebbeling说，“不论是内科医生还是心理医生，都要对精神病人出现明显的生理性疾病提高警惕。”

High Risk Of Chronic Health Conditions Plagues Those With Schizophrenia

Both men and women with schizophrenia are significantly more likely to have one or more of 46 common chronic health conditions than individuals without mental illness, according to research published in the November 2006 issue of the Journal of General Internal Medicine.

"This work is yet another piece in the larger puzzle of understanding the relationships between mental and physical health," said Caroline Carney Doebbeling, M.D., M.Sc., associate professor of psychiatry and medicine at the Indiana University School of Medicine and a research scientist at the Regenstrief Institute, Inc. Dr. Carney Doebbeling is the first author of the study which looked at inpatient and outpatient insurance claims data from more than 700,000 adults between the ages of 18 and 64. She has previously used this data to study mental illness and cancer, mental illness and diabetes, and the likelihood of women with mental illness to undergo mammograms.

In the new study, Dr. Carney Doebbeling and colleagues report that compared with individuals without mental illness, persons with schizophrenia were more likely to have a greater number of conditions spanning several disease categories including cardiovascular, pulmonary, neurological, and endocrine diseases. One-third of a rather young population (average age of those with schizophrenia was 40 years old) already had three or more chronic physical health conditions needing a physician's care. Only 29 percent of people treated for schizophrenia, compared with 54 percent of controls, did not have at least one accompanying physical illness.

The impact of having medical problems in addition to schizophrenia is significant, affecting both quality of life and delivery of psychiatric and medical services.

"This work highlights the need for integrated medical and psychiatric care, and the long-term deleterious effects on physical health of living with chronic mental illness," said Dr. Carney Doebbeling. "Both physical and mental health practitioners should have a heightened awareness of the significant medical morbidity faced by persons with chronic mental illness."

http://www.medicalnewstoday.com/medicalnews.php?newsid=58792

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