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转基因小鼠的研究应用

Fig. Settlement, proliferation, and differentiation of transplanted GSCs amplified by hGDNF in EGFP transgenic mice.

For semiquantitative colony-formation assay, we prepared testicular cells from untreated control cryptorchid testis (A) and hGDNF-transfected cryptorchid testis of EGFP-transgenic mice (B). Shown are cross-sections of each testis under UV light (A and B) and low-magnification fluorescence stereomicroscopic views of testis 8 wk after transplantation of green testicular cells from control testis (C) and hGDNF-transfected testis (D). Bar = 100 μm (A and B) and 1 mm (C and D)

原文出处：
Dramatic Expansion of Germinal Stem Cells by Ectopically Expressed Human Glial Cell Line-Derived Neurotrophic Factor in Mouse Sertoli Cells
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