Sidney Altman:RNA在生物学的中心地位及常用药物
The central role of RNA in biology and as a general therapeutic agent
Sidney Altman
(Yale University, USA)
美国耶鲁大学的Sidney Altman 教授,1989年诺贝尔化学奖得主
The diverse roles of different RNA molecules discovered over the past 20 years show the importance in intracellular biochemistry and in the regulation of developmental events in vivo. These novel functions of RNA are in addition to the basic roles of tRNA and rRNA in protein synthesis. RNA, or modifi ed versions thereof, can be shown to inhibit the expression of genes in vitro or in vivo. A new function of RNA in general gene therapy in bacteria will be discussed.
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