第11届国际胃肠道肿瘤学协会年会ISGO
【会议时间】
2014年10月23日—2014年10月24日
【会议地点】
美国 阿灵顿
【大会简介】
Welcome to ISGO
Promoting worldwide cooperation and collaboration in structural genomicsSuccess of the genome sequencing projects and major advances in methods of protein structure determination have led the structural biology community to propose the large scale mapping of protein structure space. This structural genomics initiative aims at the discovery, analysis and dissemination of three-dimensional structures of protein, RNA and other biological macromolecules representing the entire range of structural diversity found in nature. Such a complete knowledge will facilitate fundamental understanding and applications in biology, agriculture and medicine. The three-dimensional structures will be crucial for rational drug design, for advancing catalysis in chemistry and biotechnology, and for diagnosis and treatment of disease, as well as for advancing basic principles of biology. A broad collection of structures will provide valuable biological information beyond that which can be obtained from individual structures. This opportunity is made possible by rapid progress in several related key technologies. These include the construction of synchrotrons and high-field NMR instruments, the MAD method of phase determination, high throughput cloning and recombinant expression, a flood of information from genome sequencing projects, and bioinformatic methods for fold assignment, model building, and prediction of function.