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- 请问,为什么BSP只能扩增300-500bp产物
- 请问我想研究两个具有不同的SNP甲基化酶对基因组修饰 ...
- 无法
- 发放范围
- 很好的学习材料
- 很受用
- MeDIP-Seq能发现有差异的具体哪个基因吗?
- HRM的引物怎么设计啊
- 你好 我只想看一下甲基化水平在各组间有没有差异 做MSP可以 ...
- 收费怎么样?
- 您好,我想要咨询一下,BSP绘制了圆点图后最终的甲基化 ...
- 你好,请问测序reads在不同基因功能元件上的分布为 ...
- diffscoredelta beta 这两个是如何来的,它 ...
- 焦磷酸测序一般一个反应多少钱啊
- 看不懂
- MSP后的pcr,目的条带很暗,而且周围很模糊,什么原 ...
- 如果只是想针对某几个特定基因做甲基化,选择哪种或几种 ...
- 蛮好的,谢谢
- i learned. it is useful. i am going to undert ...
- diffscore怎么计算的
- 谢谢分享!
- 挺好的学习材料!
- 还不错
- 非常不错!谢谢!
Cartoon representation of select mouse (Mm), Arabidopsis (At), and Zebrafish (Dr)
Cartoon representation of select mouse (Mm), Arabidopsis (At), and Zebrafish (Dr)proteins involved in maintenance methylation, de novo methylation, and demethylation.
The MmDnmt3 family and AtDRM2 contain DNA methyltransferase domains (DNA MTase); in AtDRM2 the catalytic motifs are rearranged. The MmDnmt3 proteins also possess a cysteine rich domain that contains a Plant Homeodomain (PHD) zinc finger motif and is referred to as an ATRX-DNMT3-DNMT3L (ADD) domain. MnDnmt3a/b possess a Proline-Tryptophan-Tryptophan-Proline motif (PWWP) that MmDnmt3L lacks. AtDRM2 contains Ubiquitin Associated domains (UBA). MmMIWI2, MmMILI, and AtAGO4 possess a Piwi Argonaute and Zwille domain (PAZ) and a P-element induced wimpy testis domain (PIWI). MmDnmt1 and AtMET1 possess Bromo-Adjacent Homology domains (BAH) and a DNA MTase domain. MmDnmt1 also contains a cysteine rich (CXXC) domain. MmUHRF1 and the AtVIM family contain SET or RING associated (SRA), ring finger E3 ubiquitin protein ligase (RING), and PHD domains. MmUHRF1 also has a Tudor domain and a ubiquitin domain (UBQ). MmLSH1 and AtDDM1 contain DEAD and HELICc helicase domains. AtCMT3 contains a DNA MTase, a Chromatin Organization Modifier (CHROMO) and a BAH domain. AtSUVH4,5, and 6 possess an SRA and a histone methyltransferase domain (Histone MTase). The AtDME/ROS1 family of glycosylases all possesses a helix-hairpin-helix-Gly-Pro-Asp domain (HhH-GDP), a 4Fe-4S cluster (FES), a domain with similarity to histone H1 (H1), and a domain of unknown function (DUF). MmMBD4 contains a HhH-GDP domain and a methyl CpG binding domain (MBD); MmTDG contains a Uracil-DNA glycosylase domain (UDG). Mouse and Zebrafish AID and APOBEC proteins all contain a apolipoprotein B mRNA editing enzyme domain (APOBEC). * indicates activity on additional substrates 145
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